TABLE 3.
Results of multivariate regression analysis for children aged 2 to 10 years
| Explanatory variable | Result of regression analysis for malaria outcome |
|||||
|---|---|---|---|---|---|---|
| Whether malaria was experienced |
Time to first malaria episode |
Malaria incidence |
||||
| OR (95% CI) | P | HR (95% CI) | P | IRR (95% CI) | P | |
| Age (yr) | 0.78 (0.63-0.95) | 0.02 | 0.86 (0.80-0.94) | <0.001 | 0.91 (0.86-0.96) | 0.001 |
| Gender | 2.04 (0.76-5.46) | 0.16 | 1.38 (0.94-2.03) | 0.10 | 1.03 (0.82-1.30) | 0.80 |
| Ethnicity, Bambara | 0.23 (0.03-2.08) | 0.19 | 0.68 (0.34-1.34) | 0.26 | 1.12 (0.79-1.58) | 0.52 |
| Ethnicity, Sarakole | 0.84 (0.08-8.96) | 0.89 | 1.00 (0.49-2.06) | 0.99 | 1.53 (1.07-2.18) | 0.02 |
| Distance lived from clinic (km) | 0.30 (0.004-24.02) | 0.59 | 0.48 (0.07-3.23) | 0.45 | 0.77 (0.23-2.59) | 0.67 |
| Bed-net usea | 0.70 (0.25-1.97) | 0.50 | 0.89 (0.59-1.35) | 0.59 | 0.96 (0.75-1.23) | 0.77 |
| HbAS type | 0.23 (0.06-0.87) | 0.03 | 0.41 (0.21-0.79) | 0.01 | 0.43 (0.27-0.68) | <0.001 |
| HbAC type | 0.56 (0.16-1.95) | 0.36 | 0.81 (0.47-1.40) | 0.44 | 1.14 (0.80-1.63) | 0.47 |
| Growth-inhibitory activityb | 0.50 (0.30-0.85) | 0.01 | 0.80 (0.63-1.02) | 0.07 | 0.93 (0.75-1.16) | 0.53 |
a
Nightly bed-net use was self-reported at the end of the malaria season.
b
For this analysis, growth-inhibitory activity was divided into deciles, and thus the regression coefficient for this variable represents the change in malaria risk with each 10% increase in growth-inhibitory activity, holding all other independent variables constant.