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. 2009 Nov 23;78(2):618–628. doi: 10.1128/IAI.00647-09

TABLE 1.

Identified protein spot comparisons between study groups

Spot Proteinc AVRa
gi no. pI Molecular mass (kDa) Functionb Reference(s)
H/C M/C H/M
1 Actin +2.12 +1.81 +1.17 809561 5.8 39.45 STR 25
2 Actin +2.39 +2.04 +1.17 49868 5.8 39.45 STR 25
3 Albumin +3.26 +1.88 +1.73 19353306 5.8 70.73 APP 25
4 Albumin +2.84 +1.71 +1.66 33859506 5.8 70.73 APP 25
5 Albumin +2.83 +1.73 +1.63 19353306 5.8 70.73 APP 25
6 Albumin −2.13 −1.51 −1.41 26341396 5.5 67.04 APP 25
7 Aldehyde dehydrogenase 9 +2.87 +1.90 +1.51 9910128 6.6 54.47 ROX 17, 64
8 Annexin 5 +4.52 +2.17 +2.08 6753060 4.8 35.78 SIG 43
9 ATPS −2.05 −1.88 −1.09 23272966 5.2 56.65 EGM 11, 25
10 ATPS −2.13 −1.72 −1.24 23272966 5.2 56.65 EGM 11, 25
11 Betaine homocysteine methyltransferase 2 +3.80 +2.54 +1.50 62533211 6.0 40.28 MYL 20, 59
12 Brain and reproductive organ-expressed protein +3.04 +2.08 +1.46 38173925 5.7 43.95 APO 12, 36
13 Carbamoyl phosphate synthase −2.60 −1.87 −1.39 73918911 6.5 165.8 EGM 25, 60
14 Chaperonin-containing TCP-1 theta subunit −2.85 −1.78 −1.60 5295992 5.4 60.06 PRF 1, 25
15 Collagen 6a1 +17.8 +12.2 +1.45 12805443 5.8 44.76 STR 19, 25
16 Collagen 6a1 +47.8 +32.3 +1.48 12805443 5.8 44.76 STR 19, 25
17 Collagen 6a1 +55.8 +36.2 +1.54 12805443 5.8 44.76 STR 19, 25
18 Collagen 6a1 +47.8 +31.9 +1.50 12805443 5.8 44.76 STR 19, 25
19 Collagen 6a1 +34.7 +24.2 +1.43 12805443 5.8 44.76 STR 19, 25
20 Collagen 6a1 +21.0 +15.5 +1.36 12805443 5.8 44.76 STR 19, 25
21 Collagen 6a1 +10.2 +7.81 +1.30 12805443 5.8 44.76 STR 19, 25
22 Collagen 6a1 +5.38 +4.94 +1.09 12805443 5.8 44.76 STR 19, 25
23 Collagen XIV +5.13 +2.40 +2.13 30420885 5.0 194.3 STR 19, 25
24 Collagen XIV +4.27 +2.78 +1.54 30420885 5.0 194.3 STR 19, 25
25 Collagen XIV +7.13 +3.61 +1.97 30420885 5.0 194.3 STR 19, 25
26 DMDH −2.04 −1.71 −1.20 59808083 7.8 97.44 CHO 25
27 DMDH −2.21 −1.74 −1.27 59808083 7.8 97.44 CHO 25
28 DMDH −2.34 −1.76 −1.33 59808083 7.8 97.44 CHO 25
29 EH −2.46 −1.78 −1.38 15929294 5.9 63.07 XBM 44
30 EH −2.41 −2.03 −1.19 15929294 5.9 63.07 XBM 44
31 EH −2.82 −1.85 −1.52 15929294 5.9 63.10 XBM 44
32 10-FTHFDH −2.52 −1.49 −1.69 20380027 5.6 99.55 MYL 33, 64
33 10-FTHFDH −2.56 −1.43 −1.79 20380027 5.6 99.55 MYL 33, 64
34 10-FTHFDH −2.28 −1.54 −1.48 23271467 5.6 99.55 MYL 33, 64
35 10-FTHFDH −2.36 −1.51 −1.56 20380027 5.6 99.55 MYL 33, 64
36 10-FTHFDH −2.47 −1.70 −1.46 23271467 5.6 99.55 MYL 33, 64
37 Glucosidase II β +3.53 +2.47 +1.43 57013837 4.4 59.74 PRF 2, 49
38 Glucosidase II β +2.47 +2.13 +1.16 57013837 4.4 59.74 PRF 2, 49
39 Group-specific component +2.89 +1.81 +1.60 51172612 5.4 55.18 APP 40, 55
40 Keratin D +2.43 +1.52 +1.60 293682 5.3 47.47 STR 9, 53
41 Lymphocyte cytosolic protein 1 (plastin 2) +4.17 +3.06 +1.36 26326929 5.2 70.77 PRF 57
42 Plastin 2 +3.24 +2.45 +1.32 26326929 5.2 70.77 PRF 57
43 MUP −8.11 −1.69 −4.80 53271 4.8 17.71 PHE 18
44 MUP −7.54 −1.50 −5.02 12851568 4.8 17.71 PHE 18
45 MUP −10.3 −2.61 −3.96 13276755 4.8 17.71 PHE 18
46 MUP −5.56 −2.35 −2.37 494384 4.8 17.71 PHE 18
47 MUP −3.51 −1.50 −2.34 38488789 4.8 21.73 PHE 18
48 Myosin light polypeptide 6 −2.15 −1.68 −1.28 33620739 4.6 17.09 STR 66
49 NADH dehydrogenase (ubiquinone) Fe-S protein 1 −2.12 −1.75 −1.21 21704020 5.5 80.76 EGM 8
50 Protein disulfide-isomerase A3, Erp57 +3.17 +1.94 +1.63 26353794 5.8 57.12 ROX 25, 54
51 Pyruvate carboxylase −3.44 −2.17 −1.58 26346581 6.1 103.8 EGM 24, 25
52 Pyruvate carboxylase −2.35 −1.72 −1.36 26346581 6.1 103.8 EGM 24, 25
53 Retinol binding protein type I +2.73 +1.91 +1.43 21730472 5.1 15.86 APP 61
54 RNase/angiogenesis inhibitor +2.15 +2.16 −1.00 14577933 4.6 51.21 IMM 14
55 S-Adenosylhomocysteine hydrolase −2.10 −1.68 −1.25 63471580 6.1 48.08 MYL 35
56 SARDH −2.16 −1.35 −1.59 26352359 6.4 57.84 CHO 37
57 SARDH −2.80 −1.46 −1.92 26352359 6.4 57.84 CHO 37
58 SARDH −6.43 −3.23 −1.99 26352359 6.4 57.84 CHO 37
59 SBP2 −3.66 −2.40 −1.53 188848341 5.8 53.16 XBM 25, 28
60 SBP2 +2.99 +1.63 +1.84 18848341 6.0 52.90 XBM 25, 28
61 Succinate dehydrogenase Fp subunit −2.33 −1.81 −1.29 15030102 6.2 59.27 EGM 8
62 Transferrin +2.83 +1.43 +1.98 62027488 7.0 78.87 APP 25
63 Transferrin +4.17 +1.66 +2.52 62027488 7.0 78.87 APP 25
64 Transferrin +4.72 +1.71 +2.76 62027488 7.0 78.87 APP 25
65 Transferrin +4.60 +1.68 +2.74 62027488 7.0 78.87 APP 25
66 Tropomyosin 3 +2.19 +1.61 +1.37 26341416 4.7 27.88 STR 25, 46
67 Valosin-containing protein +4.76 +3.68 +1.29 26350783 5.1 80.70 PRF 68
68 Vimentin +2.31 +2.67 −1.16 31982755 4.9 53.73 STR 9, 25
69 Vimentin +2.54 +2.68 −1.06 31982755 4.9 53.73 STR 9, 25
70 Aldehyde dehydrogenase A1 −2.62 −2.02 −1.41 32484332 8.3 55.08 ROX 17, 64
71 Catalase 1 −3.00 −2.61 −1.15 15004258 7.8 60.01 ROX 25, 48
72 Glutamate dehydrogenase −2.76 −2.12 −1.30 26354278 8.6 61.60 EGM 42, 63
73 Glutathione S-transferase pi class −3.27 −2.05 −1.59 2624496 8.3 23.52 XBM 25, 26
74 H2 Q4 +5.01 +3.23 −1.55 51770518 7.3 71.74 IMM 22, 29
75 H2 Q4 +8.09 +4.88 −1.66 51770518 7.3 71.74 IMM 22, 29
76 H2 Q4 +12.2 +7.29 −1.67 51770518 7.3 71.74 IMM 22, 29
77 H2 Q4 +18.3 +11.6 −1.58 51770518 7.3 71.74 IMM 22, 29
78 H2 Q4 +17.2 +10.4 −1.66 51770518 7.3 71.74 IMM 22, 29
79 sm-Phosphoenolpyruvate carboxykinase +14.4 +8.05 −1.79 74828716 6.8 71.46 GLN 5
80 Prohibitin 2 +3.25 +1.61 +2.02 61556754 (76363295) 9.8 33.29 PRF 6, 41
a

AVR: average volume ratio between study groups (C, control; M, MSS; H, HSS).

b

APO, antiapoptotic; APP, acute-phase protein; CHO, choline metabolism; EGM, energy metabolism; GLN, gluconeogenesis; IMM, immune response; MYL, methylation; PHE, pheromone; PRF, protein folding; PRM, protein metabolism; ROX, redox reactions; SIG, cell signaling; STR, structural protein; XBM, xenobiotic metabolism.

c

ATPS, ATP5 beta synthetase; DMDH, dimethylglycine dehydrogenase; EH, epoxide hydrolase; 10-FTHFDH, formyl tetrahydrofolate dehydrogenase; SARDH, sarcosine dehydrogenase; H2 Q4, MHC class I H2 Q4 alpha chain.