Skip to main content
. 2009 Nov 23;78(2):872–883. doi: 10.1128/IAI.00427-09

FIG. 7.

FIG. 7.

(A) Specific growth inhibition (SGI) index of antibody-dependent cellular inhibition (ADCI) of parasite growth by total IgG purified from sera of mice immunized with MSP-Fu24, PfMSP119, PfMSP-311, or a mixture of PfMSP119 and PfMSP-311 formulated in Montanide ISA720 or alum. Parasites at the schizont stage were cocultured with human monocytes in the presence of purified antibodies (50 μg/ml of culture in the assay), and parasite growth was monitored after 96 h. (B) Reversal of antibody-dependent cellular inhibition of parasite growth by depletion of antigen-specific antibodies. The SGI index of ADCI of parasite growth purified from sera of mice immunized with MSP-Fu24-Montanide after incubation of antibodies with recombinant MSP-Fu24, PfMSP119, or PfMSP-311 to deplete antibodies specific to the respective antigen was determined.