TABLE 1.
ID | Age/sex | Specimen type | M. asiaticum microbiology | Risk factors/comorbidities | Isolates pre-M. asiaticum | Isolates post-M. asiaticum | Pulmonary disease |
---|---|---|---|---|---|---|---|
1 | 52/M | Sputum | S+ C+, 4/5; S− C+, 1/5 | Asthma/COPD | Nil | Nil | Present |
2 | 73/F | Sputum | S++, 3/3; C+; subsequent multiple positive cultures | BE, COPD | P. aeruginosa | Other NTM, Aspergillus, Acinetobacter, A. xylosoxidans | Present |
3 | 79/M | Sputum | S−; C+, 10/04; S− C+, 2/5 | COPD, previous Dukes C bowel cancer | NTM | S. aureus, S. maltophilia, P. aeruginosa | Possible |
4 | 55/M | Sputum | S− C+ | COPD | Other NTMb | P. aeruginosa | Possible |
5 | 28/F | Sputum | S− C+ | CF, ABPA | Other NTM, P. aeruginosa, Aspergillus sp., S. aureus | P. aeruginosa, S. aureus | Possible |
6 | 77/F | Sputum | S, NA; C+ | BE, GERD | Other NTM, H. influenzae | P. aeruginosa, Proteus mirabilis | Possible |
7 | 85/M | Br wash | S− C+ | NSCLC | Nil | Nil | Possible |
8 | 72/M | Br wash | S− C+ | HBV, NSCLC | Nil | Nil | Possible |
9 | 52/M | Br wash | S− C+ | None | Nil | Nil | No |
10 | 38/M | Sputum | S, NA; C+ | Non-IV drug use | Nil | Nil | No |
11 | 68/M | Sputum | S− C+ | DM, COPD | Nil | NTM | No |
12 | 62/F | Sputum | S− C+ | TB | M. tuberculosis | Nil | No |
13 | 46/F | Sputum | S− C+ | Nil | Nil | No | |
14 | 77/F | Br wash | S− C+ | BE, DM | Nil | Nil | No |
15 | 83/M | Br wash | S− C+ | Asthma/COPD | Nil | MAC, S. aureus, Aspergillus sp. | No |
16 | 76/F | Sputum | S++ C+ | DM | NTM | NA | |
17 | 52/M | Br wash/sputum | S− C+, 2/04; S− C+, 10/04 | COPD | NTM | S. maltophilia, P. aeruginosa, S. aureus | No |
18 | 37/F | Sputum | S− C+ | Alcoholism, COPD, BE | Nil | Nil | No |
19 | 25/M | Sputum | S+ C+ | Nil | Nil | No | |
20 | 84/M | Sputum | S− C+ | Previous TB? | Nil | Nil | No |
ABPA, allergic bronchopulmonary aspergillosis; BE, bronchiectasis; Br wash, bronchial washings; C, culture; CF, cystic fibrosis; COPD, chronic obstructive pulmonary disease; Cz, ceftazidime; DM, diabetes mellitus; F, female; GERD, gastroesophageal reflux disease; HBV, hepatitis B virus; ID, patient identification number; IV, intravenous; M, male; MAC, Mycobacterium avium complex; NA, not available; NSCLC, non-small cell lung cancer; NTM, nontuberculous mycobacteria; S, smear; S. maltophilia, Stenotrophomonas maltophilia; 2/04, February 2004; 10/04, October 2004; 2/05, February 2005.
The most common other NTM were MAC and unspeciated slow growers. Others included M. smegmatis, M. gordonae, M. kubicae, and M. peregrinum.