Figure 1.

Competitive displacement of [³H]PGE₂ binding to subcellular fractions from porcine adult myometrium and newborn brain by prostaglandins and analogs: fractions 1 (a) and 4 (b) from myometrium and fractions 1 (c) and 4 (d) from brain. Fraction 1 contained plasma membrane and fraction 4 contained nuclear membrane. Membranes were incubated with 10 nM [³H]PGE₂ and increasing concentrations of prostaglandins and analogs. ○, PGE₂; ■ AH6809; ♦, Butaprost; •, M&B 28,767; ▴, AH23848B. Each point is mean ± SE of three experiments, in duplicate.