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Colonic tissue sections. Colonic tissue sections from (A) a normal BALB/c mouse and (B) an IL-10−/− mouse with grade 3 histopathology. (C) Presence of crypt abscess (arrow) in colonic tissue section from an IL-10−/− mouse with intestinal pathology. (D) Colonic weight and (E) numbers of IELs from normal BALB/c mice and age-matched IL-10−/− mice with intestinal pathology; mean values ± sem of 18 mice.
