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Localization of VEGF mRNA in mouse testis. (a, c) Section through a normoxic testis showing VEGF staining predominantly in spermatoid cells (arrows) localized within tubuli. (b, d) Corresponding section through a hypoxic (CO-treated) testis. Note the predominant VEGF staining of Sertoli cells at the border of the tubuli (arrowhead). Bright-field images (×50, c, d) show the area depicted in the dark-field images (×25, a, b).
