Table 2.
| Table 2a. Associations between subject characteristics (categorical) and preference for treatment associated with severe side effects | |||
|---|---|---|---|
| Characteristic | Percent Preferring Treatment (N) | P value | |
| Race | White | 50 (41) | 0.7 |
| Other | 53 (31) | ||
| Gender | Male | 48 (57) | 0.05 |
| Female | 71 (15) | ||
| Marital status | Married | 39 (13) | 0.1 |
| Not married | 55 (59) | ||
| Education | Some college | 49 (31) | 0.6 |
| No college | 53 (41) | ||
| Employment status | Employed | 43 (23) | 0.1 |
| Unemployed | 57 (49) | ||
| Site | Veteran | 47 (45) | 0.1 |
| Nonveteran | 61 (27) | ||
| Health status | Excellent/very good | 40 (12) | 0.2 |
| Good/fair/poor | 55 (60) | ||
| Mental illness | No | 48 (41) | 0.4 |
| Yes | 55 (30) | ||
| Degree of fibrosis | Mild/none | 29 (17) | 0.0001 |
| Moderate | 61 (41) | ||
| Severe | 93 (14) | ||
| Genotype | 1 | 49 (54) | 0.03 |
| 2 | 74 (17) | ||
| Alcohol use | Never | 58 (29) | 0.2 |
| Ever | 48 (43) | ||
| Drug abuse | Never | 53 (10) | 0.9 |
| Ever | 51 (62) | ||
| Table 2b. Associations between subject characteristics (continuous) and preference for treatment associated with severe side effects. | |||
|---|---|---|---|
| Median (range) | |||
| Characteristic | Subjects preferring treatment (N=72) | Subjects not preferring treatment (N=68) | P value |
| Age | 52 (23–64) | 53 (26–70) | 0.1 |
| HCV-related quality of life | 28 (0–77) | 14 (0–84) | 0.03 |
| Expectation of developing cirrhosis | 50 (0–100) | 33 (0–100) | <0.0004 |
| Social support | 62 (5–100) | 63 (12–100) | 0.7 |
| Trust in physician | 57 (36–68) | 55 (34–68) | 0.2 |
| Decisional conflict | 25 (0–58) | 34 (0–73) | 0.02 |