Figure 2.
Western blot analysis of P-gp protein expression in placental brush border membrane samples from wild type (wt/wt) and variant (wt/var, var/var) genotypes (mean ± SEM of 199 individual samples). (A) C1236T Variants had 11% lower P-gp protein expression than wild type. (B) C3435T and (C) G2677T/A variants each had a significant 16% reduction in placental P-gp protein expression compared with wild type (p < 0.05).


