Table 4.
EI GC-MS analysis of TMS derivatives of the oxidation products of fatty acids produced by human P450 4F11.
| Substrate | [M+] | Major fragment ions | Product |
|---|---|---|---|
| C16:0 | 416 | 103/311/385/401 a | ω-OH |
| C18:1 | 444 | 103/339/413/429 | ω-OH |
| C20:4 | 472 | 103/367/441/457 | ω-OH |
| C22:6 | 500 | 103/395/469/485 | ω-OH |
| 3-OH C16:0 | 504 | 103/399/489 | ω-OH |
A GC-mass spectrum of the hydroxylation product is shown in Supplemental Data Fig. S2.