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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: Dev Biol. 2009 Nov 6;337(2):303–312. doi: 10.1016/j.ydbio.2009.10.046

Figure 1. Loss of function of either 14-3-3 isoform can enhance Yki-induced eye overgrowth.

Figure 1

(A-L′) Side views (A-L) or dorsal views (A′-L′) of adult eyes of GMR-Gal4 (A and A′), GMR-Gal4 UAS-Yki (B and B′), GMR-Gal4 UAS-Yki; UAS-14-3-3εRNAi (C and C′), GMR-Gal4 UAS-Yki; UAS-14-3-3ζRNAi (D and D′), GMR-Gal4 UAS-Yki; UAS-14-3-3

εRNAi/UAS-HA-14-3-3ζ(E and E′), GMR-Gal4 UAS-Yki; UAS-14-3-3ε

RNAi/UAS-HA-14-3-3ε(F and F′), GMR-Gal4 UAS-Yki; UAS-14-3-3ζ

RNAi/UAS-HA-14-3-3ε(G and G′), GMR-Gal4 UAS-Yki; UAS-14-3-3ζ

RNAi/UAS-HA-14-3-3ζ(H and H′), GMR-Gal4 UAS-Yki (I and I′), GMR-Gal4 UAS-Yki; 14-3-3εj2B10/+ (J and J′), GMR-Gal4 UAS-Yki; 14-3-3ζ12BL/+ (K and K′) and GMR-Gal4 UAS-Yki; 14-3-3εj2B10/+ 14-3-3ζ12BL/+ (L and L′). Reduction of 14-3-3 either by RNAi knockdown or loss of function mutations enhanced the overgrown phenotype caused by Yki overexpression.