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. Author manuscript; available in PMC: 2011 Mar 10.
Published in final edited form as: Eur J Pharmacol. 2009 Dec 16;629(1-3):31–39. doi: 10.1016/j.ejphar.2009.12.005

Figure 2. Experiment 1: Spontaneous alternation performance during systemic saline and tacrine administration.

Figure 2

Behavioral data (Mean ± SEM) from spontaneous alternation testing for PF (n = 8) and PTD (n = 8) rats after systemic administration of saline, 0.75 and 1.50 mg/kg of tacrine. Panel A displays that across drug treatments; PTD rats were more active (entered more arms) than PF rats (P < 0.05). Panel B shows the differences between PF and PTD-rats in modified (corrected for number of arms entered) spontaneous alternation scores under the saline condition. In addition, tacrine dose-dependently improved alternation scores only in the PTD group (P < 0.01).