Figure 6.
A). Administration of the 5-HT precursor (L-5-HTP) increases hindlimb activation in both moderate (n = 18) and severely (n =9) contused rats (* p < 0.05), but has no effect on sham rats (n=6). B). Administration L-5-HTP increases weight supported steps on a treadmill in moderately contused rats by 15% over vehicle administration (* p < 0.05). The indirect agonist D-FEN has no effect on weight supported stepping. Saline injection has no effect. Data are presented as difference scores between drug response and baseline behavior.
