Table 1.

Physiologic parameters during and after hypoxia-ischemia

	Baseline	Hypoxia	21% O2	Asphyxia	Post-resuscitation
		37 min	5 min		1 hr	2 hr	3 hr
MABP (mmHg)
Saline	75 ± 5	79 ± 25	99 ± 13	23 ± 12	76 ± 8	69 ± 4	70 ± 4
PPBP-Low	75 ± 6	73 ± 20	84 ± 5	26 ± 11	65 ± 5	66 ± 5	68 ± 4
PPBP-High	69 ± 10	67 ± 8	88 ± 15	27 ± 11	54 ± 5#	53 ± 7#	54 ± 8#
Arterial PO2 (mmHg)
Saline	135 ± 18	23 ± 3	67 ± 15	11 ± 8	117 ± 10	126 ± 17	134 ± 22
PPBP-Low	134 ± 20	21 ± 3	70 ± 8	7 ± 2	131 ± 24	132 ± 21	132 ± 20
PPBP-High	127 ± 21	22 ± 4	76 ± 17	11 ± 5	115 ± 17	118 ± 17	120 ± 12
Arterial PCO2 (mmHg)
Saline	39 ± 3	38 ± 5	37 ± 10	84 ± 15	38 ± 5	40 ± 5	37 ± 5
PPBP-Low	37 ± 2	40 ± 5	38 ± 5	79 ± 12	41 ± 7	37 ± 6	37 ± 4
PPBP-High	40 ± 4	43 ± 5	40 ± 7	84 ± 11	41 ± 4	40 ± 5	41 ± 3
Arterial pH
Saline	7.40 ± 0.04	7.16 ± 0.16	7.09 ± 0.19	6.83 ± 0.10	7.33 ± 0.07	7.44 ± 0.06	7.48 ± 0.04
PPBP-Low	7.44 ± 0.04	7.25 ± 0.05	7.21 ± 0.10	6.80 ± 0.08	7.38 ± 0.07	7.46 ± 0.05	7.49 ± 0.03
PPBP-High	7.42 ± 0.03	7.22 ± 0.11	7.12 ± 0.14	6.80 ± 0.08	7.26 ± 0.15	7.40 ± 0.06	7.44 ± 0.07
Arterial glucose (mmol/L)
Saline	3.3 ± 0.9	7.9 ± 3.8	9.5 ± 5.2	14.1 ± 8.0	5.6 ± 4.1	4.1 ± 2.2	3.7 ± 1.3
PPBP-Low	3.5 ± 1.2	10.1 ± 2.2	10.8 ± 3.7	12.0 ± 4.5	7.3 ± 4.7	4.7 ± 1.8	3.9 ± 1.7
PPBP-High	2.7 ± 1.1	10.0 ± 5.4	8.9 ± 5.0	13.3 ± 7.2	6.2 ± 2.8	4.3 ± 2.2	3.4 ± 1.4
Rectal Temperature (°C)
Saline	38.4 ± 0.2	38.7 ± 0.4	38.8 ± 0.5	38.9 ± 0.5	38.8 ± 0.4	38.7 ± 0.2	38.7 ± 0.5
PPBP-Low	38.6 ± 0.5	38.6 ± 0.2	38.7 ± 0.2	38.8 ± 0.2	39.1 ± 0.3	38.4 ± 0.3	38.5 ± 0.5
PPBP-High	38.4 ± 0.5	38.8 ± 0.4	39.0 ± 0.4	39.0 ± 0.3	38.6 ± 0.4	38.8 ± 0.7	38.6 ± 0.3

^#P<0.05 vs H–I+saline