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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Sep 30;1797(2):167–176. doi: 10.1016/j.bbabio.2009.09.009

Figure 2.

Figure 2

Non-permeabilized resting neurons in culture medium showed age-related differences between neurons prepared from old and middle-age rats only at complexes I, III and IV. (A) complex I by rotenone, Middle-age curve fit : Y = 73.6 * e−0.48X + 23.2, Old: Y = 84.8 * e−0.65X + 15.0. (B) complex II by 3-nitropropionic acid, Middle-age: Y = 99.4 * e−0.11X – 3.2, Old: Y = 129 * e−0.079X -31.3. (C) complex III by antimycin A Middle-age: Y = 61.0 * e−2.75X + 37.1, Old: Y = 75.1 * e−4.4X + 24.6. (D) complex IV by KCN, Middle-age: Y = 67.1 * e−0.038X + 31.4, Old: Y = 83.6 * e−0.058X + 15.3. n = 4-6 culture slips. Figure 2D was derived from data published by Jones and Brewer, 2009. IC50 values were derived from this data and summarized in Table 2.