TABLE 3.

Rufinamide Dosing

	LABEL (FDA)	AUTHORS’ RECOMMENDATIONS
Children	Given BID: Begin 10 mg/kg/day, Increase by 10 mg/kg, every other day to 45 mg/kg/day or 3,200 mg/day (whichever is less)	Given BID or TID: Begin 15 mg/kg/day Increase by 15 mg/kg/day, every week to 45 mg/kg/day or 3,600 mg/day (whichever is less)
Adults	Given BID: Begin with 400 to 800 mg/day Increase by 400 to 800 mg every 2 days, up to a maximum of 3,200 mg/day	Given BID or TID: Begin with 1,200 mg/day Increase by 1,200 mg/day every week up to 3,600 mg/day

Abbreviations: BID, twice daily dosing; TID, three times daily dosing.

Take with food. Supplied in 200- and 400-mg scored tablets (and 100 mg in Europe), which can be administered whole, in half tablets, or crushed.