Sham (n= 10) | MI (n= 10) | P-value | |
---|---|---|---|
HR (bpm) | 270 ± 15 | 326 ± 110 | 0.18 |
FS (%) | 43.2 ± 4.5 | 16.7 ± 5.5 | <0.001 |
PWSV (mm/s) | 37.8 ± 5.3 | 20.2 ± 3.3 | <0.001 |
E-wave | 84.0 ± 11.6 | 117.6 ± 16.7 | <0.001 |
A-wave | 57.9 ± 17.5 | 23.3 ± 8.6 | <0.001 |
E/A | 1.52 ± 0.27 | 5.78 ± 2.18 | <0.001 |
EDT (ms) | 52.0 ± 6.0 | 31.3 ± 8.0 | <0.001 |
IVRT (ms) | 27.3 ± 2.6 | 24.8 ± 4.1 | 0.17 |
Data are mean ± SD; Student’s t-test.
MI, animals with myocardial infarction-induced heart failure; n, number of animals; HR, heart rate; bpm, beats per minute; FS, endocardial fractional shortening; PWSV, posterior wall shortening velocity; E-wave and A-wave, early and late diastolic mitral inflow, respectively; EDT, E wave deceleration time; IVRT, isovolumetric relaxation time.