Table 3.
Group | 6 h | 24 h | 48 h | |||
---|---|---|---|---|---|---|
Serum cholesterol(mg/dl) | Serum LDL(mg/dl) | Serum cholesterol(mg/dl) | Serum LDL(mg/dl) | Serum cholesterol(mg/dl) | Serum LDL(mg/dl) | |
Control | 108.70 ± 1.86 | 88.27 ± 0.73 | 81.54 ± 2.04 | 59.06 ± 4.17 | 60.44 ± 2.71 | 45.53 ± 0.71 |
BVSW200 | 88.32 ± 1.352c | 58.88 ± 0.792c | 84.51 ± 1.38 | 65.04 ± 0.402c | 59.39 ± 3.24 | 29.75 ± 0.762a,2b,2c |
BVSW400 | 76.26 ± 0.972c | 43.71 ± 0.792c | 57.57 ± 1.172c | 23.56 ± 0.761a,2b,2c | 55.25 ± 3.091c | 23.65 ± 0.722a,2b,2c |
BVRW200 | 93.54 ± 0.902c | 73.35 ± 0.862c | 81.62 ± 1.17 | 57.54 ± 0.742c | 68.34 ± 3.24 | 49.23 ± 0.69 |
BVRW400 | 65.58 ± 0.552c | 33.55 ± 0.852c | 60.33 ± 0.922b,2c | 25.42 ± 1.421a,2b,2c | 57.98 ± 1.411a,1b,1c | 29.32 ± 0.702a,2b,2c |
BVSA200 | 66.53 ± 0.602c | 38.74 ± 0.952c | 67.44 ± 0.702c | 36.74 ± 0.802c | 55.38 ± 1.301a,1b,1c | 31.33 ± 0.722a,2b,2c |
BVSA400 | 63.48 ± 0.702c | 39.13 ± 0.892c | 59.52 ± 0.671b,1c | 26.60 ± 0.842b,2c | 53.44 ± 2.343a,3b,1c | 28.22 ± 0.672a,2b,2c |
BVRA200 | 61.35 ± 0.801b,2c | 39.49 ± 0.702b | 59.69 ± 0.581b,2c | 33.47 ± 1.311b,2c | 54.34 ± 1.383a,3b,1c | 30.64 ± 0.722a,2b,2c |
BVRA400 | 59.61 ± 0.741b,3c | 32.19 ± 0.892b | 60.27 ± 1.431b,2c | 26.41 ± 0.972b,2c | 51.52 ± 1.413a,3b,1c | 27.61 ± 0.802a,2b,2c |
Simvastatin | 52.38 ± 0.933b,3c | 22.54 ± 1.013c | 51.20 ± 1.343b,3c | 22.75 ± 0.963b,3c | 62.29 ± 1.47 | 47.21 ± 0.68 |
Fenofibrate | 61.16 ± 0.672c | 29.73 ± 0.902c | 62.28 ± 1.432c | 33.32 ± 0.942c | 62.38 ± 1.37 | 44.73 ± 0.47 |
Values are expressed as mean ± S.D. (n = 6). Cholesterol and LDL concentrations are estimated by the standard method and the values are expressed as mg/dl serum. 1P < 0.05, 2P < 0.01, 3P < 0.001, when compared with the ccontrol group; aSimvastatin; bFenofibrate. BVRW, BVRA, BVSW, BVSA: Bauhinia variegata root water, ethanolic and Bauhinia variegata stem water and ethanolic extracts, respectively, at 200 and 400 mg/kg body weight