Skip to main content
. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: J Infect Dis. 2010 Feb 1;201(3):473–477. doi: 10.1086/649901

Figure 2.

Figure 2

Immunodominant epitopes span the entire rAls3p-N sequence. Peripheral blood mononuclear cells (PBMCs) from 12 individual donors were cultured with individual 20-mer peptides, overlapping by 10 amino acids each, spanning the length of the rAls3p-N molecule. Each individual donor (Y axis) is plotted against the sequential 20-mer peptide numbers (X axis) which induced the highest number of interferon γ (IFN-γ) spots in the enzyme-linked immunosorbent spot assay for that donor’s PBMCs. Peptides inducing responses ≥95th percentile of responses (ie, ≥2 standard deviations above the mean response to all peptides) are plotted for each donor.