Table 1.
Overview of the Most Frequently Used Insulin Sensitivity Tests
| Accuracy | Time Demand (Hours) | Notes | References | |||
|---|---|---|---|---|---|---|
| Intra-Subject CV | Correlation to Gold Standard | Clinician | Participant | |||
| EIC | 4 to 10% | Gold standard | 10 | 4 | Results is not guaranteed with an inexperienced clinician | [5, 6, 11] |
| IVGTT | 21% | 0.44 to 0.89 | 3-5 | 3-5 | Result generally requires a complex computerised solver | [8, 12, 13] |
| OGTT | 7 to 15% | 0.6 to 0.8 | 3-4 | 3-4 | Rate of appearance of glucose in plasma is relatively unknown | [5, 14, 15] |
| 2hr-OGTT | 15 to 40% | 0.45 to 0.74 | 0.5 | 2.5 | Poor repeatability in terms of re-classification rate | [7, 14, 16] |
| HOMA | 10 to 40% | -0.6 to -0.9 | 0.25 | 0.25 | Low resolution in region of clinical significance | [5, 17, 18] |
Shown are the assessed accuracies in coefficient of variation (CV=SD/mean) and correlation to the gold standard EIC; and the time demand in hours for the clinician and the participant.