Changes in food intake over the course of infection seen in mice euthanized on day 2 (A), 5 (B), or 10 (C) after infection. For mice euthanized on day 2 after infection, the total food intake is summed, whereas the amount of food consumed daily is shown for mice euthanized on day 5 or 10. (A) In mice euthanized on day 2, total food intake was greater in the acute exercise (A-EX) and chronic exercise (C-EX) groups than in the nonexercise (NON-EX) group; *P < .05. (B) Rates of food intake over time in mice euthanized on day 5 after infection revealed a treatment-by-time interaction, such that food intake rates differed among the treatment groups (P = .025). C-EX mice consumed more food than NON-EX mice; *P < .05. (C) A treatment-by-time interaction (P = .008) was observed with respect to food intake in mice euthanized on day 10 after infection. In follow-up analyses, C-EX mice consumed more food than either A-EX or NON-EX mice; *P < .05.