Table 1.
Group/dose (mg/kg/infusion) | 0 (n=10) | 0.015 (n=9) | 0.03 (n=9) | 0.06 (n=9) |
---|---|---|---|---|
Active lever responses | 14.3±2.0 | 60.9±8.8** | 79.8±7.2**,+ | 72.5±7.5** |
Inactive lever responses | 3.5±0.7 | 5.7±2.0 | 4.9±1.3 | 6.5±1.7 |
Nicotine intake (mg/kg/h) | 0.80±0.13 | 1.48±0.13+ | 2.97±0.34++,^^ | |
Body weight (g) | 269±7 | 273±4 | 267±6 | 269±8 |
p<0.01 different from 0 group
p<0.05,
p<0.01 different from 0.015 group
p<0.01 different from 0.03 group