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. Author manuscript; available in PMC: 2010 Jan 28.
Published in final edited form as: Exp Biol Med (Maywood). 2006 Mar;231(3):328. doi: 10.1177/153537020623100314

Table 2.

Human γ- and β-Globin mRNA Levels in Δεsil Transgenic Mice and Wild Type β-YAC Control Mice

% of murine α- plus ζ-globin mRNA (mean ± SD)
γ-globin mRNA during
embryonic erythropoiesis		 γ-globin mRNA during
definitive erythropoiesis		 β-globin mRNA during definitive erythropoiesis
Line Day 10 yolk sac Day 12 blood Day 12 liver Day 14 liver Day 12 liver Day 14 liver Adult blood
A 23.4 ± 2.6 21.3 ± 1.5 14.2 ± 1.5 1.1 ± 0.1 42.7 ± 1.7 62.9 ± 10.6 94.6 ± 13.9
B 25.6 ± 1.6 20.2 ± 0.6 6.9 ± 0.8 2.9 ± 0.9 28.9 ± 9.4 33.1 ± 2.1 62.7 ± 13.2
C 26.4 ± 3.5 20.8 ± 2.0 15.0 ± 2.6 4.8 ± 1.5 50.5 ± 5.4 53.5 ± 3.7 105.3 ± 15.5
Mean of Δεsil
  β-YAC lines		 25.1 ± 1.6 21.8 ± 2.1 12.0 ± 4.4 2.9 ± 1.9 40.7 ± 10.9 49.8 ± 15.2 87.5 ± 22.2
Mean of
  wild-type line		 22.5 ± 2.4 24.5 ± 6.4 17.7 ± 5.1 4.7 ± 1.2 34.9 ± 2.5 52.4 ± 6.1 99.8 ± 12.3