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Haloduracin displays greater stability than nisin at physiological pH. (a) Assessment of relative stabilities of Halα, Halβ, and nisin at pH 7.5 using HPLC and MS analysis. (b) Bioassay against Lactococcus lactis HP using the same samples as analyzed by HPLC in panel a. The day of incubation is denoted above each well. Haloduracin: upper left (blue), nisin: lower left (red), nisin standards: right (yellow).
