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. 2009 Dec 3;10(12):R138. doi: 10.1186/gb-2009-10-12-r138

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Copyright ©2009 Zhang et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Correlation of DNA methylation with age in amplicon 262. (a) Methylation of amplicon 262 in old and young individuals analyzed without considering genotypes. An age-related highly significant increase in methylation appears to be detected. (b) Distribution of A and G genotypes among old and young individuals in our study. (c) Comparison of DNA methylation in old and young individuals with the same genotypes. This panel shows a re-analysis of the data plotted in (a); error bar represent the standard deviations of the data. This representation of the data clearly indicates that there is no age-related gain of methylation in this amplicon.