TABLE 3.
Strain | Growth in ligated rabbit ileal loop model |
Growth in infant mouse model |
||||
---|---|---|---|---|---|---|
No. of CFU in cocultures |
Competitive indexb | No. of CFU in cocultures |
Competitive indexb | |||
Input | Outputa | Input | Output | |||
O395 | 1.5 × 106 | 3.9 × 108 | 11.53 | 1.33 × 105 | 4.9 × 105 | 28.3 |
N16961 | 1.5 × 106 | 4.5 × 109 | 1.06 × 105 | 1.38 × 107 |
Output is the total number of CFU in fluid accumulated in the loops plus the total number of CFU in mucosal scrapings. The total number of CFU of each strain in the mucosal scrapings was about 1/10 of the numbers in the fluid.
Competitive index was calculated as follows: (output of N16961/input of N16961)/(output of O395/input of O395), where input and output are numbers of CFU.