TABLE 3.

Comparison of human adenovirus isolates detected in raw sewage and primary effluent of the East Lansing WWTP and their closest prototypes in GenBank^a

Date (mo-yr)	Sample type	Highest scoring prototype		No. of insertions/ deletions
		Serotypeb	% Identity
Aug-2005	Raw	41**	100	0
Aug-2005	Primary	41**	100	0
Sep-2005	Raw	12*	93	3
		41**	100	0
Sep-2005	Primary	41**	100	0
Oct-2005	Raw	12*	93	3
		41**	100	0
Oct-2005	Primary	41***	99	0
Nov-2005	Raw	41	98	0
Nov-2005	Primary	12*	93	3
		41	99	1
Dec-2005	Raw	12	99	1
		2	93	6
		41	95	2
Jan-2006	Raw	41**	100	0
Jan-2006	Primary	41**	100	0
Feb-2006	Raw	3	100	0
Feb-2006	Primary	41**	100	0
Mar-2006	Raw	41**	100	0
Mar-2006	Primary	40	99	0
Apr-2006	Raw	12*	93	3
		41**	100	0
Apr-2006	Primary	12	93	3
May-2006	Raw	12*	93	3
May-2006	Primary	41**	100	0
June-2006	Raw	12*	93	3
June-2006	Primary	41**	100	0
July-2006	Raw	41**	100	0
July-2006	Primary	41**	100	0
Aug-2006	Raw	12	92	4
		41***	99	0
Aug-2006	Primary	41**	100	0
June-2007	Raw	41**	100	0
July-2007	Raw	12	98	0
July-2007	Primary	12	96	0

^aAdenovirus prototypes used in the comparison were as follows: species A, human adenovirus type 12 (AB330093), type 18 (DQ149610), and type 31 (AB330112); species B1, human adenovirus type 3 (EF494650) and type 7 (AC000018); species B2, adenovirus type 35 (AC000019); species C, adenovirus type 1 (AC000017) and type 2 (EU867481); species D, adenovirus type 8 (AB361058), type 19 (AB330133), and type 51 (AB330132); species E, adenovirus type 4 (AB330085); and species F, adenovirus type 40 (AB330121) and type 41 (EF429128).

^b*, isolates were 100% homologous to each other and were most closely related to prototype HAdV 12; **, isolates were 100% homologous to each other and to prototype HAdV 41; ***, isolates were 100 % homologous to each other and were most closely related to prototype HAdV 41.