Table 2.
Measures of diagnostic performance
| IFAT | ProtA | IgG2 | IgG1 | IgG | IgA | IgM | LPA | qPCR-Blood | qPCR-BM | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity | 0.63 | 0.72 | 0.65 | 0.34 | 0.47 | 0.3 | 0.23 | 0.6 | 0.5 | 0.58 |
| 95% CI | 0.43, 0.79 | 0.57, 0.83 | 0.52, 0.77 | 0.19, 0.53 | 0.32, 0.63 | 0.15, 0.5 | 0.1, 0.46 | 0.49, 0.71 | 0.36, 0.64 | 0.34, 0.79 |
| Specificity | 0.82 | 0.78 | 0.99 | 0.99 | 0.98 | 0.99 | 0.99 | 0.56 | 0.99 | 0.98 |
| 95% CI | 0.56, 0.94 | 0.52, 0.92 | 0.88, 1 | 0.88, 1 | 0.86, 1 | 0.88, 1 | 0.88, 1 | 0.35, 0.75 | 0.88, 1 | 0.83, 1 |
| Accuracy | 0.68 | 0.73 | 0.76 | 0.54 | 0.62 | 0.52 | 0.47 | 0.59 | 0.65 | 0.78 |
| 95% CI | 0.56, 0.8 | 0.63, 0.83 | 0.68, 0.84 | 0.45, 0.63 | 0.53, 0.71 | 0.43, 0.61 | 0.38, 0.57 | 0.5, 0.68 | 0.56, 0.73 | 0.67, 0.89 |
| PPV | 0.89 | 0.91 | 0.99 | 0.98 | 0.99 | 0.98 | 0.97 | 0.75 | 0.99 | 0.97 |
| 95% CI | 0.78, 1.01 | 0.84, 0.99 | 0.96, 1.02 | 0.93, 1.03 | 0.95, 1.02 | 0.92, 1.04 | 0.9, 1.05 | 0.64, 0.85 | 0.96, 1.02 | 0.88, 1.06 |
| NPV | 0.48 | 0.45 | 0.57 | 0.41 | 0.42 | 0.4 | 0.38 | 0.39 | 0.46 | 0.7 |
| 95% CI | 0.3, 0.66 | 0.28, 0.63 | 0.45, 0.69 | 0.31, 0.51 | 0.31, 0.54 | 0.3, 0.5 | 0.28, 0.47 | 0.26, 0.53 | 0.35, 0.57 | 0.55, 0.85 |
| LR+ | 3.54 | 3.23 | 48.24 | 24.82 | 29.43 | 22.01 | 17.33 | 1.36 | 37 | 29 |
| 95% CI | 1.23, 10.17 | 1.34, 7.77 | 3.06, 760.5 | 1.55, 396.34 | 1.86, 464.62 | 1.37, 352.65 | 1.07, 279.83 | 0.9, 2.04 | 2.34, 585.33 | 1.83, 460.12 |
| LR− | 0.46 | 0.36 | 0.35 | 0.67 | 0.53 | 0.71 | 0.78 | 0.72 | 0.51 | 0.43 |
| 95% CI | 0.29, 0.72 | 0.23, 0.58 | 0.26, 0.48 | 0.57, 0.79 | 0.43, 0.66 | 0.61, 0.83 | 0.68, 0.88 | 0.48, 1.07 | 0.41, 0.63 | 0.27, 0.68 |
| DOR | 7.78 | 8.85 | 136.71 | 36.85 | 55.12 | 30.91 | 22.32 | 1.9 | 73 | 67.67 |
| 95% CI | 4.03, 15.01 | 3.64, 21.55 | 66.6, 280.64 | 17.94, 75.68 | 26.85, 113.1 | 15.02, 63.6 | 10.8, 46.14 | 0.33, 11.01 | 35.71, 149.2 | 31.18, 146.8 |
| Youden's | 0.45 | 0.49 | 0.64 | 0.32 | 0.46 | 0.28 | 0.22 | 0.16 | 0.49 | 0.56 |