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Tropoelastin levels are sustained in V3-overexpressing ASMCs. Bar graph represents elastin mRNA levels from northern blots of both control (white columns) and V3-overexpressing (black columns) rat ASMC monolayer cultures after 18 or 30 days in vitro (n = 3). Expression of tropoelastin mRNA by LX ASMCs diminishes significantly after 30 days (p < 0.01), but is maintained by LV3 ASMCs. ASMCs, arterial smooth muscle cells. V3, versican splice variant 3.
