Table 2.
Cox proportional hazards analysis of baseline variables associated with a return to urate-lowering drug use within the first year after an interruption in therapy after controlling for health plan.
| Variable Associated with Return to Therapy | |
|---|---|
| Hazard Ratio (95% CI) | |
| Demographics | |
| Gender (Male is reference) | 0.92 (0.82-1.04) |
| Age in years (<45 is the reference) | |
| 45-54 | 1.37 (1.14-1.65) |
| 55-64 | 1.26 (1.05-1.53) |
| 65-74 | 1.38 (1.15-1.66) |
| 75 and older | 1.19 (0.98-1.45) |
| Gout care | |
| Duration of urate-lowering drug use prior to the gap (lowest quartile of use is the reference) | |
| second quartile of use | 1.45 (1.26-1.68) |
| third quartile of use | 2.15 (1.86-2.48) |
| fourth quartile of use | 1.92 (1.69-2.19) |
| Use of acute gout medications | |
| NSAIDs | 0.84 (0.75-0.93) |
| Glucocorticoids | 0.83 (0.74-0.93 |