Table 3.
All potential confounding factors that were considered in this study
| Demographic factors | ||
|---|---|---|
| Age | Calendar year | Gender |
| Nursing home resident | Race | State |
| Chronic Diseases | ||
| Chronic kidney disease | Diabetes | Liver disease |
| Obesity | Prior history of GI bleed | |
| Drugs that could potentially increase or decrease the bleeding risk | ||
| Aspirin | Histamine H-2 antagonists | Proton pump inhibitors |
| NSAIDs | ||
| Drugs that could potentially interact with warfarin* | ||
| Acetaminophen | Amiodarone | Azathioprine |
| Azithromycin | Butalbital | Carbamazepine |
| Ciprofloxacin | Clarithromycin | Co-trimoxazole |
| Dexamethasone | Diltiazem | Doxycycline |
| Erythromycin | Fluconazole | Fluvoxamine |
| Gatifloxacin | Levofloxacin | Levothyroxine |
| Methimazole | Methylprednisolone | Metronidazole |
| Phenobarbital | Phenytoin | Prednisone |
| Primidone | Quinidine | Quinine |
| Sertraline | Troglitazone | Tetracycline |
| Trazodone | Zafirlukast | |
| Potential CYP2C9, CYP3A4, and/or CYP1A2 inhibitors or inducers† | ||
| Nefazodone | Pioglitazone | Verapamil |
Based on potentially interacting drugs according to Drug Facts and Comparison (Class 1 and 2 drugs)
Only CYP2C9, CYP3A4, and/or CYP1A2 inhibitors or inducers that were not listed as drugs that could potentially interact with warfarin in Drug Facts and Comparison