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. 2010 Jan 29;5(1):e8524. doi: 10.1371/journal.pone.0008524

Figure 2. Survival curves of mice treated therapeutically with anidulafungin, caspofungin, micafungin.

Figure 2

Percent survival for treated vs untreated mice was calculated for the 21 day treatment period using GraphPad Prism v.4. Asterisks indicate a significant difference from untreated controls (C/S). Line colors reflect the treatment and regimen as shown on the figure legend. Panel A: 10 mg/kg treatment regimen: anidulafungin: P = 0.02; caspofungin: P = 0.006; micafungin: P = 0.0006; T/S: 0.002. Panel B: 5 mg/kg treatment regimen: anidulafungin: P = 0.002; T/S: P = 0.02; Panel C: 2.5 mg/kg regimen: anidulafungin: P = 0.004; T/S: P = 0.002; Panel D: 1.0 mg/kg regimen: anidulafungin: P = 0.0049; caspofungin: P = 0.002; T/S: P = 0.002; Panel E: 0.5 mg/kg regimen: anidulafungin: P = 0.002; caspofungin:P = 0.007; T/S: P = 0.002; Panel F: 0.1 mg/kg regimen: anidulafungin: P = 0.004; T/S: P = 0.002.