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. 2010 Jan 29;5(1):e8955. doi: 10.1371/journal.pone.0008955

Figure 6. TWEAK induces nuclear translocation of p52 and RelB in vivo.

Figure 6

A) p100/p52 immunohistochemistry 24 h following TWEAK or vehicle injection. Nuclear p52 is observed in renal tubules from mice treated with TWEAK (arrows). Original magnification ×400. Detail ×1000. Pictures representative of 6/7 animals per group. B) RelB immunohistochemistry 24 h following TWEAK or vehicle injection. Nuclear RelB is observed in tubules from mice treated with TWEAK (arrows). Original magnification ×400. Detail ×1000. Controls for the technique are stained with non-specific IgG. Nuclear staining is present in samples stained with specific anti-p100/52 and anti-RelB as compared with the isotype control. Pictures representative of 6/7 animals per group.