Skip to main content
. 2010 Jan 29;5(1):e8955. doi: 10.1371/journal.pone.0008955

Figure 7. TWEAK modulates kidney CCL21 expression in vivo.

Figure 7

A) TWEAK treatment of healthy mice increases kidney CCL21a mRNA at 24 h. RNA obtained from the whole kidney. Real time RT-PCR. Mean ±SEM of 6/7 animals per group. *p<0.05 vs control 24 h. B) Increased kidney CCL21 protein induced by TWEAK as assessed by Western blot. Mean ± SEM of 6/7 animals per group. *p<0.05 vs control 24 h. C) CCL21 protein localized to tubular epithelium of kidneys 24 h following TWEAK injection. Original magnification ×200. Detail ×400. Controls for the technique are stained with non-specific IgG. D) Quantification of CCL21 staining as mean ± SEM of 5 animals per group. *p<0.04 vs control.