Table 4.
Cox regression analysis for hospital, with and without adjustment for ER status and IMD for those with 1–3 nodes positive in patients aged <70 years
Factor | Category | Relative hazard and 95% CI |
|
Univariate, unadjusted | Multivariate, mutually adjusted | ||
ER status | Negative | 1.00 (–) | 1.00 (–) |
Positive | 0.30 (0.22–0.40) | 0.31 (0.23–0.41) | |
Not known | 0.77 (0.55–1.08) | 0.73 (0.51–1.03) | |
IMD score | Trend per 10% | 1.10 (1.03–1.28) | 1.10 (0.99–1.22) |
Hospital | 1 | 1.00 (–) | 1.00 (–) |
2 | 2.09 (1.15–3.78) | 1.76 (0.97–3.20) | |
3 | 1.21 (0.72–2.02) | 1.07 (0.63–1.80) | |
4 | 1.09 (0.69–1.73) | 1.01 (0.63–1.61) | |
5 | 1.28 (0.71–2.29) | 1.10 (0.60–2.00) | |
6 | 1.53 (0.91–2.56) | 1.38 (0.82–2.31) | |
7 | 1.66 (1.02–2.71) | 1.47 (0.89–2.40) | |
8 | 2.22 (1.27–3.88) | 1.75 (0.96–3.18) | |
9 | 2.05 (1.20–3.49) | 1.61 (0.94–2.77) | |
10 | 1.64 (0.96–2.79) | 1.46 (0.84–2.52) | |
Significance of hospital differences | P = 0.03 | P = 0.8 |
ER, estrogen receptor; IMD, Index of Multiple Deprivation; CI, confidence interval.