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. Author manuscript; available in PMC: 2011 Jan 5.
Published in final edited form as: J Biomech. 2009 Oct 6;43(1):38. doi: 10.1016/j.jbiomech.2009.09.007

Figure 2.

Figure 2

Illustration of cell traction forces (CTFs) generated during cell migration. Actin polymerization facilitates protrusion of the leading edge that is accompanied by traction forces exerted across nascent focal complexes and mature focal adhesions (Wiesner et al.) (Wiesner et al.). Forward protrusion in concert with contraction of the rear cell body overcomes ECM resistive adhesive tractions to allow forward cell migration.