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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: J Mol Cell Cardiol. 2009 Jul 24;48(1):191. doi: 10.1016/j.yjmcc.2009.07.017

Figure 3.

Figure 3

Representative Ito traces recorded from an Epi (Panel A) and an Endo cell (Panel B) under control conditions and in the presence of NS5806 (10 μM). The voltage clamp protocol is shown at the top of the figure and Cd2+ was present to block ICaL. Mean I-V relation for peak Ito from Epi (Panel C), Mid (Panel D) and Endo cells (Panel E) in absence and presence of NS5806 (10μM). The density of Ito was greater in Epi and Mid cells and application of NS5806 caused a substantial increase in the magnitude of Ito.