. Author manuscript; available in PMC: 2011 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2009 Oct 24;48(2):395. doi: 10.1016/j.yjmcc.2009.10.004

Table 1.

Effects of Palmitate:BSA(30:60 µM) on K⁺ Currents in WT, SWAP and Kv2.1^−/− LVA myocytes¹

	n	I_peak (pA/pF)	I_to,f		I_K,slow		I_ss (pA/pF)	I_K1 (pA/pF)
	n	I_peak (pA/pF)	Density (pA/pF)	τ_decay (ms)	Density (pA/pF)	τ_decay (ms)	I_ss (pA/pF)	I_K1 (pA/pF)
WT
Control	24	54 ± 2	32 ± 1	50 ± 2	16 ± 1	1004 ± 45	5.5 ± 0.3	21 ± 2
Palmitate:BSA		65 ± 2^**	35 ± 2^**	53 ± 2	22 ± 1^**	1011 ± 28	7.4 ± 0.4^**	22 ± 2
SWAP
Control	17	51 ± 3	34 ± 3	47 ± 2	12 ± 1⁺⁺	1049 ± 31	4.7 ± 0.2⁺	--
Palmitate:BSA		58 ± 3^**	38 ± 3^**	47 ± 2	14 ± 1^**	1118 ± 33	5.3 ± 0.2^**	--
Kv2.1−/−
Control	12	50 ± 3	36 ± 2	40 ± 2⁺⁺	10 ± 1⁺⁺	762 ± 33⁺⁺	3.7 ± 0.3⁺⁺	--
Palmitate:BSA		55 ± 3^**	38 ± 2^*	38 ± 1	12 ± 1^**	632 ± 24	3.7 ± 0.3	--

Currents were evoked at +40 mV from holding potential of −70 mV.

^*,**

Values in the presence of palmitate:BSA are significantly (^*P<0.05,^**P<0.01) larger than controls.

^+,++

Values are significantly (⁺P<0.05,⁺⁺P<0.01) smaller than in WT LVA cells.