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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Mol Carcinog. 2010 Feb;49(2):152–156. doi: 10.1002/mc.20584

Figure 1. E2f2 deficiency increases tumor incidence in K5.Myc transgenic mice.

Figure 1

K5.Myc transgenic mice wild type (+/+), hemizygous (+/−) or nullizygous (−/−) for E2f2 were monitored for spontaneous tumor development for one year. Tumors arising in K5-expressing epithelial tissues were recorded. The Fisher’s exact test was applied to demonstrate statistically significant differences between E2f2+/+ and E2F2+/− (p <0.05) and E2f2−/− (p <0.001) transgenic mice. The number of mice for each genotype is indicated in Table 1.