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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Gastroenterology. 2009 Sep 12;138(1):285. doi: 10.1053/j.gastro.2009.09.003

Figure 1. IGF-I expression is increased in smooth muscle cells of stricturing Crohn's disease.

Figure 1

Figure 1

Panel A: IGF-IEa RNA transcript levels are increased in muscle cells isolated from stricturing Crohn's disease compared to normal margins. Q-PCR results are expressed as fold increase over normal using the 2ΔCt method with β-actin as control. Panel B: IGF-I protein levels are increased in muscle cells isolated from stricturing Crohn's disease compared to normal margins. Results from ELISA are expressed in pg/mg protein. Values represent the mean ± SEM of 4-5 separate experiments. * denotes P < 0.05 vs normal margin.