Skip to main content
. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Gastroenterology. 2009 Oct 1;138(1):294. doi: 10.1053/j.gastro.2009.09.054

Figure 2.

Figure 2

Effects of HeCS and colonic resiniferatoxin (RTX) treatment on electrophysiological properties of DiI labeled colon-specific thoracolumbar DRG neurons. Changes in electrophysiological properties of colon specific DRG neurons from control (Ctr, n=31 neurons), HeCS (n=22 neurons), HeCS rats pretreated with RTX (n=23 neurons) and control rats treated with RTX (n=20 neurons). (A) Current clamp traces showing action potentials induced by current injection at rheobase. (B) Graph showing changes in rheobase. (C) Graph showing changes in resting membrane potential. (D) Current clamp traces showing the number of action potentials at 2X rheobase. (E) Number of action potentials (AP) induced by current injection at 2X rheobase. *p<0.05, control vs HeCS, #p<0.05 HeCS vs HeCS + RTX.