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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Gastroenterology. 2009 Sep 26;138(1):185. doi: 10.1053/j.gastro.2009.09.045

Figure 4. LPS activates the AKT-GSK3β signaling pathway in enterocytes.

Figure 4

A–E: SDS-PAGE showing expression of the indicated protein in IEC-6 cells treated with LPS at the concentrations and durations indicated (A–D) or mucosal scrapings from the terminal ileum of mice injected with saline or LPS for the durations indicated (E). All blots are representative of 3 separate experiments; over 5 mice per group in E. F: Schematic summarizing panels A–D showing mechanism by which TLR4 inhibits enterocyte proliferation.