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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Neuropharmacology. 2009 Dec 4;58(3):605. doi: 10.1016/j.neuropharm.2009.11.015

Fig. 3.

Fig. 3

Classification of LCRs and HCRs and cell surface DATs in striatal synaptosomes prepared 30 min post-cocaine in these rats. A Distribution of baseline and the initial 25 min of cocaine-induced locomotor activity in rats subsequently classified as either LCRs or HCRs. The solid horizontal line represents this group’s median cocaine-induced locomotor activity. B Representative Western blot for DAT in the total (tot) and biotinylated (bio) fractions from an LCR, HCR and veh-treated rat. Bottom panel: Surface DAT values for all LCRs (n = 10), HCRs (n = 10) and veh-treated rats (n = 11), expressed as a percentage of their respective tot value. C Correlation of distance traveled 25 min post-cocaine and surface DAT values 30 min post-cocaine for all cocaine-treated rats. Bars in (A) and (B) are means ± SEM.