Table 2.
Comparison of Author's Interpretations of Their Heterogeneity of Treatment Effects (HTE) Analysis and the Strength of Evidence for Clinicostatistical Divergence (CSD)
| Strength of Evidence for Clinicostatistical Divergence |
||||||
|---|---|---|---|---|---|---|
| Authors' Interpretation of Their HTE Analysis Results | Unable to Classify | None | Weak | Moderate | Strong | Total |
| Evidence for HTE was sufficient to support different treatment recommendations in one or more subgroups | 0 | 2 | 4 | 1 | 3 | 10 |
| Evidence for HTE was insufficient to support differential treatment recommendations but sufficient to warrant further systematic research | 10 | 6 | 10 | 5 | 0 | 31 |
| Evidence for HTE was present but not enough to warrant differential treatment recommendations or further systematic research | 0 | 0 | 0 | 0 | 1 | 1 |
| Evidence for HTE was absent | 6 | 2 | 8 | 2 | 2 | 20 |
| No interpretation of HTE-related results | 13 | 6 | 3 | 3 | 0 | 25 |
| Total | 29 | 16 | 25 | 11 | 6 | 87 |
Note. Numbers represent number of trials.