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. Author manuscript; available in PMC: 2010 Jan 29.
Published in final edited form as: J Invest Dermatol. 2009 Apr 2;129(9):2156. doi: 10.1038/jid.2009.61

Figure 5. Epitope mapping of pathogenic 3–30/3h mAb.

Figure 5

Wild-type and domain-swapped extracellular domains of human desmoglein 1 (Dsg1) and Dsg3, and of Dsg1 and Dsg2 produced by baculovirus expression system were used for immunoprecipitation with 3–30/3h mAb. The molecular structure of domain-swapped molecules is shown. The results of immunoprecipitation assays with 3–30/3h mAb are listed in the right panel.