Skip to main content
. Author manuscript; available in PMC: 2010 Jan 29.
Published in final edited form as: J Invest Dermatol. 2009 Apr 2;129(9):2156. doi: 10.1038/jid.2009.61

Figure 7. Majority of anti-desmoglein 3 (Dsg3) antibody binding in PV sera targets the mature form more than the precursor form of Dsg1.

Figure 7

(a) Coomassie blue staining of purified recombinant baculoproteins used for precursor and mature Dsg1 ELISA plates. White arrowhead indicates the precursor form and black arrow head indicates the mature form. (b) Binding curves of representative anti-Dsg3 mAbs (AK23, AK15) against mature and precursor Dsg3 ELISA plates. (c) Dispersion of immunoreactivity of 47 PV sera between the mature and precursor Dsg3 ELISA plates. Each closed square represents single patient. Most PV sera showed stronger reactivity against mature Dsg3 plate than against precursor Dsg3 plate.