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. Author manuscript; available in PMC: 2010 Jan 29.
Published in final edited form as: J Invest Dermatol. 2009 Apr 2;129(9):2156. doi: 10.1038/jid.2009.61

Table 1.

Epitopes and pathogenicity of anti-Dsg1 mAbs

Name of clones Epitope type Deduced epitope
Pathogenic antibody 3–30/3h Conformational aa 89–101 of Dsg1

Non-pathogenic antibodies 3–97/1c Conformational Precursor form of Dsg1
3–94/O18O8 Conformational Precursor form of Dsg1
1–18/L12 Linear EC3 of Dsg1

Abbreviations: aa, amino acid; Dsg, desmoglein; EC, extracellular domain.