Table 2.
Dimensions of DSM-IV/CIDI MDE lifetime onset, course, and 12-month persistence and severity by age among NCS-R respondents with MDE
| Age Groups |
Age Difference |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| All ages | 18-34 | 35-49 | 50-64 | 65+ | |||||||
| Est | (se) | Est | (se) | Est | (se) | Est | (se) | Est | (se) | F/χ233 | |
| I. Lifetime onset and course | |||||||||||
| Mean age of onset | 26.2 | (0.4) | 17.8 | (0.2) | 25.5 | (0.6) | 33.1 | (0.6) | 43.0 | (1.6) | 696.8* |
| Mean number of lifetime episodes | 18.6 | (1.6) | 15.4 | (2.3) | 18.2 | (2.1) | 19.7 | (3.1) | 30.2 | (7.9) | 3.7 |
| (n) | (1,828) | (601) | (669) | (409) | (149) | ||||||
| II. Twelve-month persistence and severity | |||||||||||
| Mean 12-month duration (in weeks) | 27.5 | (0.7) | 26.8 | (1.0) | 27.1 | (1.3) | 28.6 | (1.8) | 32.4 | (2.7) | 1.6 |
| Clinically mild (%)1 | 8.8 | (1.0) | 8.2 | (1.6) | 6.8 | (1.5) | 10.3 | (2.0) | 21.8 | (9.6) | 7.2 |
| Clinically severe (%)1 | 48.0 | (1.9) | 45.8 | (3.0) | 53.0 | (3.1) | 45.8 | (5.4) | 37.8 | (9.6) | 8.7* |
| Severe role impairment (%)2 | 65.5 | (2.3) | 62.6 | (3.1) | 72.2 | (3.1) | 61.3 | (5.7) | 56.5 | (7.8) | 9.9* |
| Mean days out of role | 43.1 | (4.2) | 28.3 | (3.5) | 54.4 | (9.0) | 58.4 | (11.5) | 18.8 | (4.6) | 8.3* |
| (n) | (805) | (322) | (280) | (162) | (41) | ||||||
Significant age difference at the .05 level, two-sided test.
The percent of cases whose depression was classified either severe or very severe on the self-report version of the Quick Inventory of Depressive Symptomatology (Rush et al., 2003)
The percent of cases whose depression-related role impairment was classified either severe or very severe on any dimension of the Sheehan Disability Scales (Leon et al., 1997)
Significance was evaluated with an F test for the means (age of onset, mean number of lifetime episodes, mean duration) and a χ2 test for the proportions (the percent of cases classified clinically mild, clinically severe, and having severe role impairment)