Fig. 8.

Docking results using HADDOCK on EIN-HPR. The scoring results of the final 200 water-refined EIN-HPR complex models are shown here. The interaction zone (active residues) is defined using ¹⁵ N–¹ H chemical shift perturbation (CSP) data on EIN(Garrett et al. 1997b) and HPR (van Nuland et al. 1995). a The correct assignment of EIN and HPR is used to define the active residues from the CSP data (see Fig. 7a). b The assignment ensemble of EIN, obtained by NOEnet using NOE-data and ¹⁵ N–¹ H chemical shifts (Case 4 of Table 3), is used to define the active residues on EIN (see Fig. 7b)