Table 2.
Multivariable-adjusted prevalence odds ratios for surgically-diagnosed endometriosis and adenomyosis according to baseline characteristics that would precede disease development in the California Teachers Study.
| |
Endometriosis diagnosed during study 1995-2003 |
Adenomyosis diagnosed during study 1995-2003 |
||||
|---|---|---|---|---|---|---|
| No endometriosis | Endometriosis | Multivariable adjusted POR (95% CI)*a | No adenomyosis | Adenomyosis | Multivariable adjusted POR (95% CI)*a | |
| Age at baseline (years) | ||||||
| 25-29 | 4754 | 15 | 0.57 (0.33, 0.99) | 4772 | 9 | 0.10 (0.05, 0.19) |
| 30-39 | 14201 | 87 | 1.08 (0.81, 1.42) | 14287 | 137 | 0.50 (0.41, 0.61) |
| 40-49 | 20862 | 122 | 1.0 | 23129 | 441 | 1.0 |
| 50-59 | 3447 | 5 | 0.25 (0.10, 0.61) | 17324 | 208 | 0.64 (0.54, 0.76) |
| 60-69 | - | - | - | 11753 | 123 | 0.57 (0.47, 0.70) |
| 70-79 |
- |
- |
- |
7103 |
43 |
0.34 (0.24, 0.46) |
| Race/Ethnicity | ||||||
| White | 35963 | 192 | 1.0 | 67235 | 825 | 1.0 |
| Black | 976 | 7 | 1.38 (0.65, 2.97) | 1921 | 20 | 0.82 (0.53, 1.29) |
| Latina | 2992 | 14 | 0.88 (0.51, 1.52) | 3860 | 58 | 1.26 (0.96, 1.66) |
| Asian/Pacific Island | 1994 | 11 | 1.11 (0.60, 2.04) | 3162 | 33 | 0.83 (0.58, 1.18) |
| Other |
1339 |
5 |
0.70 (0.29, 1.71) |
2190 |
25 |
0.95 (0.64, 1.43) |
| Mother or sister with endometriosis | ||||||
| No | 39610 | 194 | 1.0 | 73264 | 886 | 1.0 |
| Yes | 2788 | 30 | 2.12 (1.44, 3.12) | 3763 | 62 | 1.25 (0.96, 1.63) |
| Adopted |
866 |
5 |
1.19 (0.49, 2.92) |
1341 |
13 |
0.84 (0.49, 1.47) |
| Age at menarche (years) | ||||||
| ≤10 | 2891 | 9 | 0.52 (0.26, 1.05) | 5229 | 101 | 1.59 (1.26, 2.01) |
| 11 | 6412 | 41 | 1.08 (0.74, 1.59) | 11829 | 139 | 1.00 (0.81, 1.22) |
| 12 | 12162 | 59 | 0.83 (0.59, 1.16) | 21432 | 268 | 1.07 (0.91, 1.27) |
| 13 | 12991 | 75 | 1.0 | 23561 | 276 | 1.0 |
| 14 | 5319 | 30 | 1.00 (0.65, 1.53) | 9911 | 113 | 1.00 (0.81, 1.27) |
| ≥15 | 3489 | 15 | 0.78 (0.44, 1.36) | 6406 | 64 | 0.89 (0.68, 1.18) |
|
Ptrend |
|
|
.68 |
|
|
.004 |
| Time to regular menstrual periods | ||||||
| <12 months | 19931 | 120 | 1.0 | 39330 | 495 | 1.0 |
| 12-23 months | 8909 | 36 | 0.67 (0.46, 0.98) | 16107 | 170 | 0.83 (0.70, 0.99) |
| ≥24 months | 11189 | 60 | 0.92 (0.67, 1.26) | 16795 | 232 | 1.10 (0.93, 1.29) |
| Never regular, unknown | 3235 | 13 | 1.09 (0.48, 2.46) | 6136 | 64 | 0.95 (0.64, 1.41) |
|
Ptrend |
|
|
.88 |
|
|
.18 |
| Length of menstrual cycle (days) | ||||||
| ≤24 | 1993 | 17 | 1.47 (0.88, 2.47) | 3932 | 68 | 1.46 (1.13, 1.89) |
| 25-26 | 3746 | 10 | 0.46 (0.24, 0.88) | 7261 | 89 | 1.08 (0.86, 1.36) |
| 27-28 | 18246 | 105 | 1.0 | 34744 | 410 | 1.0 |
| 29-30 | 10294 | 57 | 0.97 (0.70, 1.35) | 18159 | 232 | 1.10 (0.93, 1.29) |
| 31-32 | 3710 | 23 | 1.09 (0.69, 1.72) | 5721 | 76 | 1.08 (0.84, 1.39) |
| ≥33 | 2435 | 8 | 0.57 (0.27, 1.19) | 3395 | 35 | 0.82 (0.58, 1.17) |
| Unknown | 2840 | 9 | 5156 | 51 | ||
|
Ptrend |
|
|
.70 |
|
|
.13 |
| Body mass index at age 18 (kg/m2) | ||||||
| ≤19.1 | 8361 | 44 | 0.85 (0.57, 1.28) | 14999 | 178 | 0.98 (0.79, 1.20) |
| 19.2-20.2 | 8468 | 41 | 0.79 (0.52, 1.20) | 15396 | 189 | 0.98 (0.80, 1.21) |
| 20.3-21.3 | 8189 | 50 | 1.0 | 14854 | 187 | 1.0 |
| 21.4-23.0 | 7888 | 30 | 0.63 (0.40, 0.99) | 14262 | 187 | 1.04 (0.85, 1.28) |
| ≥23.1 | 9286 | 56 | 1.01 (0.69, 1.48) | 15738 | 194 | 0.96 (0.78, 1.17) |
| Unknown | 1072 | 8 | 3119 | 26 | ||
| Ptrend | .50 | .49 | ||||
*
POR, prevalence odds ratio; CI, confidence interval.
a
Adjusted for the other variables in the table.